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过多地消耗酒精是一种加重慢性肝病病情的因素.人们发现酒精性与非酒精性慢性肝病的r-谷氨酰转移酶(GGT)、丙氨酸移换酶(AST)、天冬氨酸移换酶(ALT)活性和红细胞的平均体积(MCV)都升高,因此,由以上各项试验不易将酒精性与非酒精性慢性肝病区别开来.作者提出:酒精性慢性肝病患者的红细胞中5-氨基-4-酮戊酸脱水酶(5-ALAD)的活性下降,并且5-ALAD与GGT、MCV三项试验的组合是检测酒精性的排除非酒精性的慢性肝病最好的试验组合.本文对患慢性肝病(经活检证实)的一组205例病人(88例酒精性和117例非酒精性)使用荧光
Excessive consumption of alcohol is a factor that aggravates the condition of chronic liver disease.It has been found that alcohol-induced and non-alcoholic chronic liver disease, r-glutamyl transferase (GGT), alanine exchange enzyme (AST), aspartate Acid exchange enzyme (ALT) activity and the average volume of red blood cells (MCV) are elevated, therefore, from the above test is not easy to distinguish alcoholic and non-alcoholic chronic liver disease.The authors propose: alcoholic chronic liver disease patients The activity of 5-amino-4-ketopentanoate dehydratase (5-ALAD) in erythrocytes decreased, and the combination of 5-ALAD with GGT and MCV tests was the best for detecting alcoholic non-alcoholic chronic liver disease Experimental combination.This article uses a series of 205 patients (88 alcoholics and 117 non-alcoholics) with chronic liver disease (confirmed by biopsy) using fluorescence