目的:探讨血液透析患者透析过程中低血压的发病危险因素及预后。方法:收集四会市人民医院2015年4月至2016年4月收治的血液透析患者78例作为研究对象,根据患者透析3个月内发生低血压的情况进行分组对比,即透析中发生低血压组和未发生低血压组各39例,观察两组患者的相关指标,分析低血压的发病危险因素。结果:未发生低血压组在透析前收缩压、透析前平均动脉压(MAP)、甲状旁腺激素(PTH)、总胆固醇、失重干体质量比方面的指标均优于发生低血压组的相应指标,差异具有统计学意义(P<0.05)。未发生低血压组患者的平均年龄和透析时间均低于发生低血压组患者相应数据,差异具有统计学意义(P<0.05)。未发生低血压组患者的并发症发生率为5.12%,1年后死亡率为5.12%,发生低血压组分别为28.19%和20.51%,组间比较,差异具有统计学意义(P<0.05)。结论:血压透析患者中透析中低血压的发病危险因素主要有:年龄、透析前收缩压、透析龄、透析前MAP、PTH和失重干体质量比、血清总胆固醇(TC),故建议临床针对这些危险因素制定有效的干预措施,保证患者的生命安全。 Objective: To investigate the risk factors and prognosis of hypotension during dialysis in hemodialysis patients. Methods: 78 cases of hemodialysis patients admitted from April 2015 to April 2016 in People’s Hospital of Sihui City were collected and compared according to the occurrence of hypotension within 3 months of dialysis in patients, ie hypotension during dialysis 39 cases in each group and none in hypotension group. The related indexes of two groups were observed and the risk factors of hypotension were analyzed. Results: Before hypotension, systolic blood pressure, pre-dialysis mean arterial pressure (MAP), parathyroid hormone (PTH), total cholesterol, weight-loss dry weight ratio indicators were better than those in the hypotension group Indicators, the difference was statistically significant (P <0.05). The mean age and dialysis duration of patients with hypotension were lower than those of patients with hypotension, the difference was statistically significant (P <0.05). The incidence of complications in patients without hypotension was 5.12%, the mortality after 1 year was 5.12%, the incidence of hypotension was 28.19% and 20.51% respectively. There was significant difference between the two groups (P <0.05) . Conclusions: The risk factors of dialysis hypotension in patients with hemodialysis are: age, pre-dialysis systolic blood pressure, dialysis age, pre-dialysis MAP, PTH and weight-loss dry weight ratio, serum total cholesterol (TC) These risk factors to develop effective interventions to ensure the safety of patients.