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目的：比较国产与进口硝苯地平缓释片（ＳＲＮ）治疗原发性高血压的疗效。方法：将９５例高血压病人分为２组，国产组５０例［男性３５例，女性１５例，年龄（６３±ｓ１２）ａ］，应用国产ＳＲＮ，２０ｍｇ，ｐｏ，ｂｉｄ；进口组４５例［男性３０例，女性１５例，年龄（６２±１４）ａ］。应用进口ＳＲＮ２０ｍｇ，ｐｏ，ｂｉｄ。２组疗程均为２０ｄ。结果：国产ＳＲＮ组与进口ＳＲＮ组的降压总有效率分别为９４％和９８％，Ｐ＞０．０５；２组降压幅度与心率加快幅度比较，Ｐ＞０．０５。不良反应发生率分别为４０％和４２％，Ｐ＞０．０５，但均较轻微，不须停药。结论：国产与进口ＳＲＮ治疗原发性高血压的疗效相似。
Objective: To compare the efficacy of domestic and imported nifedipine sustained-release tablets (SRN) in the treatment of essential hypertension. Methods: Ninety-five hypertensive patients were divided into two groups, 50 cases in the domestic group (35 males and 15 females, age 63 ± s12), and the domestic SRN, 20mg, po, 30 males and 15 females, age (62 ± 14) a]. Application of imported SRN20mg, po, bid. 2 groups of treatment are 20d. Results: The total effective rate of domestic and imported SRN SRN were 94% and 98%, respectively, P> 0.05; 2 sets of blood pressure and heart rate acceleration rate, P> 0.05. The incidence of adverse reactions were 40% and 42%, respectively, P> 0.05, but were minor, without stopping. Conclusion: The therapeutic effects of domestic and imported SRN on essential hypertension are similar.