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对原发性舍格林氏综合征患者唾液及血清白细胞介素-6含量进行测定,结合临床表现以确定患者唾液白细胞介素-6水平能否反映患者唾液腺受累情况及潜在的自身免疫紊乱。 材料及方法 原发性舍格林氏综合征患者31例,原发性胆汁性肝硬化患者15例,健康对照者14例。用2％柠檬酸刺激腮腺分泌并用Carlson-Crittenden杯收集唾液。用高灵敏度的ELISA法(酶联免疫吸附试验/测定唾液及血清白细胞介素-6含量。对舍格林氏综合征患者进行了血清免疫学、唾液功能及组织病理学检
The levels of salivary and serum interleukin-6 in patients with primary Sjogren's syndrome were measured, and clinical manifestations were determined to determine whether salivary interleukin-6 levels in patients with salivary glands could reflect salivary gland involvement and potential autoimmune disorders in patients. Materials and Methods 31 patients with primary Sjogren's syndrome, 15 patients with primary biliary cirrhosis and 14 healthy controls. Parotid gland secretion was stimulated with 2% citric acid and saliva was collected using the Carlson-Crittenden cup. Serum immunology, salivary function and histopathology were performed on patients with Seger's syndrome by high sensitivity ELISA (enzyme-linked immunosorbent assay / determination of saliva and serum interleukin-6 levels