论文部分内容阅读
本文测定了无症状心肌缺血（ＳＭＩ）组（１５例）、心绞痛组（１１例）和对照组（７例）运动试验前后血浆八肽胆囊收缩素（ＣＣＫ－８）、Ｐ物质含量，探讨这两种神经调节肽与ＳＭＩ和心绞痛发生的关系。结果显示：①运动前３组血浆ＣＣＫ－８含量分别为４．５５±２．１８、５．１１±１．５９和５．３９±２．８４ｐｍｏｌ／Ｌ，３组之间比较无明显差异；运动后３组血浆ＣＣＫ－８含量分别为４．９１±１．０８、８．５６±１．５７和５．７３±２．４６ｐｍｏｌ／Ｌ，心绞痛组明显高于ＳＭＩ和对照组（Ｐ＜０．０１）。②运动前３组血浆Ｐ物质含量分别为２．１３±０．２８、２．１０±０．２１和２．１３±０．１６ｎｍｏｌ／Ｌ，３组间比较无明显差异；运动后３组分别为２．２５±０．２１、２．４６±０．２０和２．１８±０．１２ｎｍｏｌ／Ｌ，心绞痛组明显高于ＳＭＩ组和对照组（Ｐ＜０．０２）。结果表明：高血浆ＣＣＫ－８、Ｐ物质含量可能参与心绞痛的发生，心肌缺血时无症状可能与血浆ＣＣＫ－８、Ｐ物质含量未升高有关。
The content of plasma octotokinin (CCK-8) and substance P before and after exercise test in asymptomatic myocardial ischemia group (15 cases), angina pectoris group (11 cases) and control group (7 cases) The relationship between these two neuromodulating peptides and the occurrence of SMI and angina pectoris. The results showed that: (1) The content of CCK-8 in the three groups before exercise was 4.55 ± 2.18, 5.11 ± 1.59 and 5.39 ± 2.84 pmol / L, respectively. There was no significant difference among the three groups. The levels of plasma CCK-8 in the three groups after exercise were 4.91 ± 1.08, 8.56 ± 1.57 and 5.73 ± 2.46 pmol / L, respectively, and those in angina group were significantly higher than those in SMI group and control group .01). ② The content of substance P in the three groups before exercise was 2.13 ± 0.28, 2.10 ± 0.21 and 2.13 ± 0.16 nmol / L, respectively. There was no significant difference between the three groups after exercise 2.25 ± 0.21,2.46 ± 0.20 and 2.18 ± 0.12nmol / L, respectively. The angina group was significantly higher than the SMI group and the control group (P <0.02). The results showed that the content of CCK-8 and P in high plasma may be involved in angina pectoris. Asymptomatic myocardial ischemia may not be related to the increase of plasma CCK-8 and P contents.