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目的:了解我院外科手术围术期抗菌药物的使用现状,并对其使用的合理性进行评价。方法:随机抽取我院2010年1～6月外科手术治疗的住院病历480份,调查不同切口类型手术围手术期预防使用抗菌药物的情况。对抗菌药物的选择、适应证、术前用药时间、联合用药与疗程等进行评价。结果:围手术期患者抗菌药物应用率为100.0%,预防性抗菌药物选用起点过高;抗菌药物预防术后感染时间超过标准的比例为67.5%(324/480),联合用药的比例为45.8%(220/480),均超过国家标准。结论:我院外科围手术期抗菌药物应用趋向于规范,但还存在选药档次偏高、术后预防应用时间偏长等问题,需要继续加强围手术期抗菌药物使用的督导。
Objective: To understand the status of perioperative antibiotic use in our hospital and to evaluate the rationality of its use. Methods: A total of 480 inpatients with surgical treatment from January to June 2010 in our hospital were selected randomly to investigate the prevention of the use of antimicrobial agents during perioperative period in different types of incisions. The choice of antibacterial drugs, indications, preoperative medication time, combined with medication and treatment evaluation. Results: The application rate of antibacterials in perioperative period was 100.0%, and the starting point of prophylactic antibacterials selection was too high. The proportion of antibacterials in prevention of postoperative infection exceeded the standard was 67.5% (324/480), and the rate of combination therapy was 45.8% (220/480), all exceeding the national standard. CONCLUSION: The application of perioperative antibiotics in our hospital tends to be standardized, but there are still some problems such as the high grade of drug selection and the long time of prevention and treatment after operation. It is necessary to continue to supervise the use of antibiotics in perioperative period.