Cooling panels are increasingly used in domestic residential buildings.To provide medium temper-ature cold water for the cooling panel,and dehumidify the indoor air simultaneously,a new kind of temperature-humidity independent control air-conditioning unit was developed for single residential house by utilizing multi-variable technology.First,the supply air temperature was studied to determine the proper supply air flow rate for the humidity control.Then,the energy consumption of different temperature-humidity independent eontrol systems was studied.The analysis indicates that unity evaporating temperature can be used to handle the mois-ture load and sensible heat load in two evaporators.So the unit scheme was put forward.Two evaporators were used to produce medium temperature water and dry air separately,and electric expansion valves were used to control the refrigerant distribution between the two evaporators.Then, experimental work was carried out to in-vestigate the influence of compressor frequency,refrigerant distribution on the dehumidification capacity,energy efficiency and refrigeration capacity.In the end,the paper concludes that both compressor frequency and refrig-erant distribution can control the dehumidification capacity,but the former influences the EER more than the latter.while the latter influences the refrigeration capacity more than the former.We can find a proper running point at certain sensible and latent cooling load by adjusting both compressor frequency and electric expansion.valve.The energy consumption of this kind of unit was estimated and compared with present room air condition-ers,which shows that it can save about 41% cooling energy consumption.