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对不同临床类型的乙型肝炎患者，采用捕捉法ＥＬＩＳＡ，以ＩｇＭ和ＩｇＧ类抗体排除抗原性异物的免疫反应进行比较研究。结果发现，两种反应能力在慢性ＨＢＶ感染中基本相同，表现出明显的病型差异，而在急性ＨＢＶ感染中则不同，前者反应强度显著高于后者；二者阳性率在慢性ＨＢＶ感染的临床类型中虽均随其肝损害加重而显著上升，但ＩｇＧ／Ｃ３双特异性循环免疫复合物（ＴＣＩＣ）与ＡＬＴ有关，而ＩｇＭ／Ｃ３－ＴＣＩＣ与ＡＬＴ无关；二者阳性率与Ｃ４的关系亦不同。这些结果提示，ＩｇＭ和ＩｇＧ／补体－ＴＣＩＣ的病理意义不同，免疫复合物的异质性值得注意。
For different clinical types of hepatitis B patients, the use of capture ELISA, IgM and IgG antibodies to exclude antigenic foreign body immune response were compared. The results showed that the two response capacity in chronic HBV infection is basically the same, showing a significant difference in the type of disease, but in acute HBV infection is different, the former was significantly higher than the latter; the positive rate in chronic HBV infection However, IgG / C3 bispecific circulating immune complex (TCIC) was associated with ALT, whereas IgM / C3-TCIC was not associated with ALT. The positive rates of C4 / C4 Also different. These results suggest that the pathological significance of IgM and IgG / complement-TCIC are different, and the heterogeneity of immune complexes is worth noting.