黄芪皂苷甲是从中药黄芪中分得的成分。体外实验中,对兔红细胞膜有稳定作用。口服或静脉注射均能对抗组胺和5-羟色胺引起的大鼠毛细血管通透性增加。口服可抑制角叉菜胶引起的大鼠踺底肿胀。静脉注射引起麻醉猫或大鼠的血压明显下降,此作用不为苯海拉明或阿托品所阻断。用恒压泵法测外周血管阻力,股动脉给药可引起猫后肢血管扩张。 Astragaloside A is obtained from the traditional Chinese medicine Astragalus ingredients. In vitro experiments, the rabbit erythrocyte membrane has a stabilizing effect. Oral or intravenous injection can antagonize histamine and serotonin-induced rat capillary permeability increased. Oral administration of carrageenan can inhibit the swelling of the cat bottom. Intravenous injection of cats or rats caused by anesthesia significantly decreased blood pressure, this effect is not blocked by diphenhydramine or atropine. Constant pressure pump method to measure peripheral vascular resistance, femoral artery administration can cause cat dilated vasodilation.