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评述生物微机电系统和生物芯片的最新进展 :能够在液体中操纵单个细胞的微型机器人和生物分子电机驱动的纳米器件代表了当前生物微机电系统的最新成就。使用纳米粒子探头的扫描 DNA检测技术和把生物分子亲和识别信息转换为纳米机械变形的检测技术是 2种全新的生物芯片检测技术 ;蛋白质芯片在后基因组时期将发挥重要作用 ;带有扩散阱阵列的纳米流体分离器件、集成纳升 DNA分析器件和细胞电穿孔芯片则分别反映了生物芯片在分离新模式、微分析系统集成和细胞控制方面的研究现状。单元尺寸趋向纳米量级及系统集成度不断提高是总的发展趋势
Recent advances in bio-MEMS and biochips: Micro-robots and biomolecular motor-driven nanodevices capable of manipulating individual cells in liquids represent the latest achievements of current bio-MEMS systems. Scanning DNA detection using nanoparticle probes and detection techniques that convert biologically compatible affinity recognition information to nanomechanical deformation are two novel biochip detection technologies; protein chips will play an important role in the post-genome era; with diffusion wells The arrays of nanofluidic devices, integrated nanoliter DNA analysis devices and electroporation cells, respectively, reflect the current status of biochip research in separation models, microanalysis system integration, and cell control. Unit size tends to nano-scale and continuous improvement of system integration is the general trend of development