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目的 :探讨恶性淋巴瘤与葡萄糖 - 6 -磷酸脱氢酶 (G6 PD)之关系。方法 :G6 PD检测采用分光光度计酶活性法。结果 :与正常人相比恶性淋巴瘤 G6 PD活性显著增高 (P<0 .0 1) ,G6 PD缺乏率显著增高 (P<0 .0 5 ) ,儿童 G6 PD活性明显增高 (P<0 .0 1) ,恶性淋巴瘤进展期 G6 PD活性增高 (P<0 .0 1)。结论 :恶性淋巴瘤 G6 PD活性增高 ,且与年龄、分期有关。
Objective: To investigate the relationship between malignant lymphoma and glucose - 6 - phosphate dehydrogenase (G6 PD). Methods: G6 PD assay using spectrophotometric enzyme activity method. Results: The G6 PD activity in malignant lymphoma was significantly higher than that in normal people (P <0.01). The G6 PD deficiency rate was significantly higher in children with malignant lymphoma (P <0.05). The G6 PD activity in children with malignant lymphoma was significantly higher (P <0.01). 0 1), and the progression-promoting G6 PD activity of malignant lymphoma increased (P <0.01). Conclusion: The activity of G6 PD in malignant lymphoma is increased, and related to age and stage.