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目的 :为探索结核菌实验室药敏结果和临床疗效是否呈一致性。方法 :对痰培养阳性病人做药敏实验 ,并采取全程督导化疗方法 ,观察治疗效果。结果 :初治全敏感病人和耐药病人治愈率经统计学分析无显著性意义 ;复治全敏感和耐药病人治愈率对照无显著性意义 ;初治耐药和复治耐药病人治愈率有显著性差异 (x2 =4 .91)。结论 :实验室药敏报告由于受给药方式、体内因素多方面影响 ,与临床治疗效果并不呈一致性 ,临床用药中不应拘泥于实验室报告是否耐药 ,治疗用药史对制定新的治疗方案有较大的参考意义。
OBJECTIVE: To explore whether the drug susceptibility results and clinical efficacy of Mycobacterium tuberculosis laboratories are consistent. Methods: To test the sensitivity of sputum culture positive patients, and to guide the whole process of chemotherapy to observe the therapeutic effect. Results: The cure rate of newly diagnosed patients and drug-resistant patients was not statistically significant. The cure rate of patients with full-sensitive and resistant patients was not significantly different from the control group. The cure rate of newly diagnosed drug-resistant patients and drug-resistant patients There was a significant difference (x2 = 4.91). Conclusion: Because of the way of drug administration and the influence of various factors in the laboratory, the laboratory susceptibility report is not consistent with the effect of clinical treatment. The clinical medication should not be confined to whether the laboratory report is resistant or not. Treatment programs have a greater reference value.