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目的探讨左卡尼汀联合血液透析对老年维持性血液透析患者营养状态及生活质量的影响。方法选取安阳地区医院71例老年维持性血液透析患者,随机分为对照组35例和观察组36例,对照组给予单纯血液透析治疗,观察组于透析后静脉注射左卡尼汀1 g,均治疗6个月,观察比较两组血红蛋白(Hb)、血清白蛋白(Alb)、前白蛋白(PAB)、体质量指数(BMI)水平,并以生活质量评分量表(GQOLI-74)评估两组生活质量。结果治疗后观察组Hb(94.58±7.77)g/L、Alb(46.22±4.28)g/L、PAB(290.69±45.66)mg/L及BMI(23.28±0.30)水平均高于对照组,差异有统计学意义(P<0.05);经治疗观察组物质功能、心理功能、躯体功能及社会功能生活质量评分均高于对照组,差异有统计学意义(P<0.05)。结论左卡尼汀与血液透析联合应用于老年维持性血液透析患者,可有效提高患者生活质量,改善其营养状态。
Objective To investigate the effects of levocarnitine and hemodialysis on nutritional status and quality of life in elderly patients with hemodialysis. Methods 71 elderly patients with hemodialysis in Anyang District Hospital were randomly divided into control group (n = 35) and observation group (n = 36). The control group was treated with hemodialysis only. The observation group received intravenous levocarnitine 1 g (Hb), serum albumin (Alb), prealbumin (PAB), and body mass index (BMI) were measured and compared between the two groups for two months after treatment. The quality of life scale (GQOLI-74) Group quality of life. Results The levels of Hb (94.58 ± 7.77) g / L, Alb (46.22 ± 4.28) g / L, PAB (290.69 ± 45.66) mg / L and BMI (23.28 ± 0.30) in the observation group were significantly higher than those in the control group Statistical significance (P <0.05). The scores of physical function, psychological function, physical function and social function in the treatment group were significantly higher than those in the control group (P <0.05). Conclusion L-carnitine combined with hemodialysis in elderly patients with hemodialysis can effectively improve the quality of life of patients and improve their nutritional status.