论文部分内容阅读
目的比较慢性鼻窦炎鼻息肉患者术中及术后1,3,6个月息肉组织中真菌SIgE的浓度,评估真菌在鼻息肉发生、发展及转归中的作用。方法采用ImmunoCAP100系统,检测64例慢性鼻窦炎鼻息肉患者和30例鼻中隔偏曲患者鼻息肉组织中真菌SIgE的浓度,并行统计学分析。结果实验组术中组织、术后一月组织SIgE检测与对照组比较差异有统计学意义;实验组术中组织SIgE检测与术后1月组织比较差异有统计学意义;术后3、6个月组织SIgE检测实验组、对照组均无阳性发现。结论真菌免疫学与鼻息肉的发生发展有关,手术干预去除了窦口鼻道复合体等部位的阻塞病变,术腔的水肿、分泌物潴留得到改善,寄生真菌的黏膜损伤及变应性反应得到抑制,可改善鼻息肉的预后。
Objective To compare the concentration of fungal SIgE in patients with chronic sinusitis and nasal polyps during operation and at 1, 3 and 6 months after operation to evaluate the role of fungi in the occurrence, development and prognosis of nasal polyps. Methods ImmunoCAP100 system was used to detect the concentration of fungal SIgE in the nasal polyps in 64 patients with chronic sinusitis and nasal polyps and in 30 patients with nasal septal deviation. Statistical analyzes were performed. Results There was significant difference between the experimental group and the control group in the intraoperative tissue of SIgE and that of the control group. There was significant difference between the experimental group and the 1 month after operation The monthly tissue SIgE test group, the control group were found no positive. Conclusions Fungal immunology is related to the occurrence and development of nasal polyps. Surgical intervention removes obstructive lesions such as sinus ostiomeatal complex, edema in the cavity and retention of secretions, mucosal damage and allergic reaction of parasitic fungi Inhibition, can improve the prognosis of nasal polyps.