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已有动物实验证明,内淋巴加压可引起耳蜗微音电位(CM)急剧下降。本文则通过动物模型进一步定量研究CM下降与压力的关系。将人工内淋巴液(含KCl160mM、NaCl19mM、CaCl_21mM)注入蜗管(中阶)。通过蜗管内的电极,同时记录耳蜗静息电位(EP)和CM。另在前庭阶造孔插入玻璃电极,通过WP1压力测量系统测定耳蜗内淋巴液压力。结果表明,停止呼吸可使EP和CM下降,耳蜗内淋巴压力增加。但此压力与EP、CM下降无直接关系。当向蜗管加压注入人工内淋巴液时,EP无变化,而CM成指数倍急剧下降。使
Animal experiments have shown that endolymphatic pressure can cause cochlear microphones potential (CM) dropped sharply. In this paper, animal models were further used to quantitatively study the relationship between CM decline and stress. Intra-articular lymphatic fluid (containing KCl160 mM, NaCl19 mM, CaCl-2 mM) was injected into the scrolls (middle stage). The cochlear resting potential (EP) and CM were recorded simultaneously through the electrodes in the scroll. In addition, a glass electrode was inserted into the anterior chamber to make a determination of intra-cochlear lymph pressure by the WP1 pressure measurement system. The results showed that, to stop breathing can EP and CM decreased cochlear lymphatic pressure increased. However, this pressure is not directly related to the decrease of EP and CM. When pressure was injected into the scrotum into the artificial endolymph, EP did not change, while CM dropped exponentially sharply. Make