患者,女,76岁,因“反复头昏伴黑矇半年”于1989年诊断为病态窦房结综合征,行单腔心室按需(VVI)起搏器植入术。既往有高血压、慢性支气管炎史、青霉素过敏史。后因起搏器电池耗竭更换起搏器2次,第2次更换发生在2007年,术中测试起搏阈值升高,包埋原电极导线,在同侧植入了第2根电极导线。于2010年12月出现左上胸部起搏器囊袋皮肤红肿半个月,无发热,血白细胞计数正常,诊断为起搏器囊袋感染。入院予碘伏局部换药和头孢唑 The patient, female, 76 years old, was diagnosed as sick sinus syndrome in 1989 because of “dizziness with darkness for six months”. The single ventricle on-demand (VVI) pacemaker implantation was performed. Past history of hypertension, chronic bronchitis, history of penicillin allergy. After the pacemaker battery depletion to replace the pacemaker 2 times, the second replacement occurred in 2007, the intraoperative pacing threshold increased, embedded the original electrode lead, implanted in the ipsilateral second electrode lead. In December 2010 appear upper left chest pacemaker pouch skin irritation for half a month, no fever, normal white blood cell count, diagnosed as pacemaker pouch infection. Admission to iodophor partial dressing and cefazolin