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食管癌是一种常见的恶性肿瘤,在全球范围内的发病率和死亡率分别排在恶性肿瘤的第8位和第6位。目前食管癌临床检查主要依靠X射线钡餐、CT扫描、内窥镜/活检、细胞学检查等方法,这些常规检查需要射线/器械侵入或者有创,不适合体检或高危人群筛查。近期,中国科学院合肥物质科学研究院与中国科学院合肥肿瘤医院共同研发出一种实时在线检测呼气质谱仪——质子转移反应质谱仪(proton transfer reaction mass spectrometer,PTR-MS)。利用该质谱仪,
Esophageal cancer is a common malignancy with morbidity and mortality globally ranked 8th and 6th respectively. The current clinical examination of esophageal cancer mainly depends on X-ray barium meal, CT scan, endoscopy / biopsy, cytology and other methods, these routine tests require radiographic / instrumentation invasive or invasive, not suitable for physical examination or screening of high-risk groups. Recently, the Chinese Academy of Sciences Hefei Institute of Materia Medica and the Chinese Academy of Sciences Hefei Cancer Hospital jointly developed a real-time on-line detection of breath mass spectrometer - proton transfer reaction mass spectrometer (proton transfer reaction mass spectrometer, PTR-MS). Using this mass spectrometer,