论文部分内容阅读
组胺是机体重要的自体活性物质之一,经其各型受体介导参与多种生理病理过程。随着人类基因组计划及国际人类单体型图项目的完成,组胺相关基因多态性与疾病的关联性研究日渐成为国内外学者研究热点。本文就目前国内外关于组胺相关基因多态性研究现状进行了综述,以期为后续研究组胺相关基因与疾病的关联性提供较为系统的文献基础。
Histamine is one of the important self-active substances in the body and is involved in many physiological and pathological processes through its various receptors. With the completion of the human genome project and the international human haplotyping project, the study of the association between histamine-related gene polymorphisms and diseases has increasingly become a hot topic both at home and abroad. This review summarizes the current research status of histamine related gene polymorphism at home and abroad, in order to provide a systematic literature basis for the follow-up study of the association between histamine-related genes and diseases.