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目的 :追踪观察鼻咽癌患者放疗辅加局部化疗后 ,鼻咽局部病灶复发率及 1～ 5年生存率。方法 :试验组 13 8例鼻咽癌患者放疗辅加 5 Fu局部化疗 ,对照组 13 8例鼻咽癌患者在放疗前给一疗程BPF方案诱导化疗 ,两组病人均定期追踪观察。结果 :试验组和对照组鼻咽癌局部复发率分别为 9 4%和 3 0 4% ,5年生存率分别为 70 5 %和 5 4 4%。结论 :本法可减少鼻咽癌患者鼻咽局部病灶复发率 ,并可提高鼻咽癌患者 3～ 5年生存率
OBJECTIVE: To observe the recurrence rate of nasopharyngeal local lesions and the survival rates of 1 to 5 years after radiotherapy combined with local chemotherapy in patients with nasopharyngeal carcinoma. Methods: Thirteen patients with nasopharyngeal carcinoma radiotherapy combined with 5 Fu local chemotherapy were given in the experimental group. One hundred and thirty-eight patients with nasopharyngeal carcinoma in the control group were given chemotherapy with BPF regimen before radiotherapy. Both groups were followed up regularly. Results: The local recurrence rates of NPC and control group were 94% and 340% respectively, and the 5-year survival rates were 70.5% and 544% respectively. Conclusion: This method can reduce the recurrence rate of nasopharyngeal local lesions in patients with nasopharyngeal carcinoma, and can improve the 3- to 5-year survival rate of patients with nasopharyngeal carcinoma