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目的:观察九味消瘤散辅助治疗恶性肿瘤患者的临床疗效,同时统计其不良反应情况以评价其安全性,从而为恶性肿瘤疾病患者规范治疗提供参考。方法:186例诊断为恶性肿瘤者按照随机数字表法分为对照组与观察组,两组患者均采用水溶性维生素+复方氨基酸注射液治疗,对照组加消癌平片治疗;观察组加九味消瘤散治疗。结果:(1)两组患者中医证候积分较治疗前均明显变化,且治疗组下降较对照组显著,P<0.05;(2)观察组治疗总有效率为86.0%,明显高于对照组61.3%,P<0.05;(3)两组肿瘤进展控制有效率比较,P>0.05;(4)观察组生活质量改善情况明显优于对照组,P<0.05;(5)两组均未发生明显不良事件。结论:相比消癌平来说,采用中药九味消瘤散辅助治疗效果肯定且安全。
Objective: To observe the clinical curative effect of adjuvant treatment of malignant tumor by Jiwei Xiaoyao San, and to count the adverse reaction to evaluate its safety so as to provide reference for the standard treatment of patients with malignant tumor. Methods: 186 cases diagnosed as malignant tumor were divided into control group and observation group according to random number table. Both groups were treated with water-soluble vitamin + compound amino acid injection and control group with Xiaochangping tablet. Taste elimination tumor treatment. Results: (1) The scores of TCM syndromes in both groups were significantly changed before treatment, and the treatment group decreased significantly compared with the control group (P <0.05); (2) The total effective rate in the observation group was 86.0%, significantly higher than that in the control group 61.3%, P <0.05; (3) Comparison of the effective rate of tumor progression control between the two groups, P> 0.05; (4) The improvement of quality of life in the observation group was significantly better than that of the control group, P <0.05; Obvious adverse events. Conclusions: Compared with Xiaopengping, the effect of adjuvant treatment with Chinese medicine Jiwei Xiaoyao San is affirmative and safe.