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Combs医生问:在向一位儿子刚进大学的家长说明为何需作一次麻疹、流行性腮腺炎和风疹疫苗(MMR)的加强免疫时,我解释约5%的孩子因麻疹初免失败而需要再免。现询问如果孩子初免没有应答,再免成功的可能性有多大?有何资料表明那些初免(假定为1岁后免疫)失败的患者第二次免疫能成功?是否可能有些个体因遗传原因而不产生免疫应答,这样尽管多次免疫仍得不到保护。如果部分初免失败的人再免后仍得不到保护,那么还有什么办法可能根除麻疹的发生?
Dr. Combs asks: When explaining to a parent of a son who is going to college about the need for a booster immunization against measles, mumps and rubella (MMR), I explain that about 5% of the children are required for failing a first immunization Then free. Are there any possibilities to re-succeed if the child’s initial immunization is unanswered? What information indicates that the second immunization could be successful in those patients who failed in the initial immunization (assumed to be immunization after 1 year of age) Without generating an immune response, which is not protected despite multiple immunizations. If some of those who failed in the initial immunization are still not protected, what is the possible way to eradicate measles?