论文部分内容阅读
本文对符合修正后Haüser标准的234例慢性胃溃疡癌变进行分析。发病性别和年龄分布与普通型胃癌一致,但病程长(89％在1年以上),多数(79％)有典型胃溃疡病症状。术前只有1/3病例获得正确诊断。病理巨检,多与文献所述一致;但25％的溃疡直径不足2cm,而文献常以2.5cm做为良、恶性溃疡的划界。癌变灶小,85％在溃疡一侧或双侧,提示于溃疡边缘多点活检有助于术前诊断。癌的组织学类型和影响预后的主要因素,皆与普通型胃癌一致,但其预后显然好,5年生存率67％。因此,应将慢性胃溃疡癌变单列为特殊型胃癌。
This article analyzed 234 cases of chronic gastric ulcer carcinogenesis that met the revised Haüser criteria. The incidence of gender and age distribution was consistent with that of common type of gastric cancer, but the duration of the disease was long (89% in more than 1 year), and the majority (79%) had typical gastric ulcer symptoms. Only 1/3 of cases were correctly diagnosed before surgery. The pathological examination was mostly consistent with that described in the literature; however, 25% of the ulcers were less than 2cm in diameter, and the literature often used 2.5cm as the demarcation of benign and malignant ulcers. Small cancerous lesions, 85% in one or both sides of the ulcer, suggesting that more biopsies at the edge of the ulcer contribute to preoperative diagnosis. The histological types of cancer and the main factors affecting prognosis are the same as those of normal gastric cancer, but their prognosis is obviously good. The 5-year survival rate is 67%. Therefore, cancerous chronic gastric ulcer should be classified as special gastric cancer.