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自1914年Abel首次通过静脉切开分离血浆并采用PLa-Smapheresis这一术语。当时由于分离血浆需要5个小时,加上溶血、败血症等并发症,使这种方法的临床应用受到限制。1960年Sehwab报道,用血浆交换治疗原发性巨球蛋白血症极为有效,从此治疗性血浆交换逐渐被注意。六十年代末研制出血细胞分离机,可能分离血液的细胞成份和大量血浆。七十年代末出现膜式分离装置,除了设备的发展和更新外,人们对疾病的认识和知识也不断增加,所以
Abel first isolated plasma by phlebotomy in 1914 and adopted the term PLa-Smapheresis. At that time, due to the separation of plasma requires 5 hours, coupled with hemolysis, sepsis and other complications, so that the clinical application of this method is limited. Sehwab reported in 1960, plasma exchange for the treatment of primary macroglobulinemia is extremely effective, from the therapeutic plasma exchange gradually pay attention. Developed at the end of the sixties hemorrhagic cell separator, may separate the blood cell components and a large amount of plasma. In the late seventies membrane separation device, in addition to the development and updating of equipment, people’s awareness and knowledge of the disease is also increasing, so