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目的:对血浆脂蛋白测定在肾功能衰竭患者治疗中的应用价值进行分析。方法:选取自2013年3月至2016年3月在茂名市人民医院接受治疗的肾功能衰竭患者50例,将其设为观察组,另选取同期在本院体检中心进行常规健康体检的同龄人群50例,设为对照组。对比分析两组患者高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、血清总胆固醇(TC)、三酰甘油(TG)、载脂蛋白A1(Apo A1)与载脂蛋白(Apo B)。结果:与正常对照组相比,观察组各项血浆脂蛋白指标均处于异常状态,且观察组HDL-C(0.87±0.41)mmol·L~(-1)、Apo A1(1.12±0.35)g·L~(-1)明显低于对照组HDL-C(1.11±0.36)mmol·L~(-1)、Apo A1(1.42±0.37)g·L~(-1);观察组LDL-C(4.17±0.78)mmol·L~(-1)、TC(6.76±2.37)mmol·L~(-1)、TG(1.89±1.99)mmol·L~(-1)、Apo B(2.97±0.57)g·L~(-1)明显高于对照组LDL-C(3.02±0.61)mmol·L~(-1)、TC(4.96±0.54)mmol·L~(-1)、TG(1.16±1.65)mmol·L~(-1)、Apo B(0.96±0.42)g·L~(-1),组间对比,差异均具有统计学意义(P<0.05)。结论:血浆脂蛋白测定对肾功能衰竭患者具有辅助诊断价值,能够为进一步的治疗提供有效依据,具有极其重要的指导意义。
Objective: To analyze the value of plasma lipoprotein assay in the treatment of patients with renal failure. Methods: Fifty patients with renal failure who were treated in Maoming People’s Hospital from March 2013 to March 2016 were selected as the observation group. Another group of patients with the same physical status The population of 50 cases, as the control group. (HDL-C), low density lipoprotein cholesterol (LDL-C), total cholesterol (TC), triglyceride (TG), apolipoprotein A1 Apolipoprotein (Apo B). Results: Compared with the normal control group, all the plasma lipoprotein indexes in the observation group were abnormal, and the levels of HDL-C (0.87 ± 0.41) mmol·L -1, Apo A1 (1.12 ± 0.35) g · L ~ (-1) was significantly lower than HDL-C (1.11 ± 0.36) mmol·L -1 and Apo A1 (1.42 ± 0.37) g · L -1 in the control group. LDL-C (4.17 ± 0.78) mmol·L -1, TC (6.76 ± 2.37) mmol·L -1, TG 1.89 ± 1.99 mmol·L -1, Apo B 2.97 ± 0.57 ) g · L -1 was significantly higher than that of LDL-C (3.02 ± 0.61) mmol·L -1, TC (4.96 ± 0.54) mmol·L -1, TG 1.16 ± 1.65) mmol·L -1 and Apo B 0.96 ± 0.42 g · L -1, respectively. The differences between the two groups were statistically significant (P <0.05). Conclusion: The determination of plasma lipoprotein in patients with renal failure has diagnostic value, which can provide an effective basis for further treatment, has an extremely important guiding significance.