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RNA编辑是一种对基因编码的mRNA进行重新修饰的过程 ,它可以通过对前体mRNA中的核苷酸进行添加、删除或修饰而产生基因序列的改变 ,进而调节受体介导的信号转导 ,产生广泛的生理效应 ,已发现在载脂蛋白B受体 (APOBR) ,5 羟色胺 2C亚型受体 ( 5 HT2CR) ,谷氨酸门控通道五个亚单位(GLURSUBUNITS)中均存在RNA编辑过程 ,并且具有编辑过程均需要特异编辑酶的作用、且其作用均具有位点和组织选择性等共同特性。RNA编辑是调节受体介导信号的重要机制。
RNA editing is a process of reprogramming gene-encoded mRNAs by generating, deleting, or modifying nucleotides in the precursor mRNA to produce changes in the gene sequence that regulate the receptor-mediated signal transduction Lead to a wide range of physiological effects have been found in the apolipoprotein B receptor (APOBR), serotonin 2C subtype 5 receptor (5 HT2CR), glutamate gated channel five subunits (GLURSUBUNITS) exist RNA Editing process, and editing process requires specific editing of the role of the enzyme, and its role has the site and tissue selectivity and other common features. RNA editing is an important mechanism for regulating receptor-mediated signals.