论文部分内容阅读
四物汤是由当归、川芎、芍药和地黄组成的方剂。作者用四物汤的甲醇和水的提取物与四种生药中各取三种组合,即A:当归、芍药、地黄;B:川芎、芍药、地黄;C:川芎、当归、地黄;D:川芎、当归、芍药的甲醇提取物以及当归、川芎、芍药、地黄的单独甲醇提取物,对正常小白鼠的毒性和致死量放射线的防护作用进行了研究。结果表明,给小白鼠口服或腹腔注射2000mg/kg四物汤甲醇提取物时未发现死亡;口服2000mg/kg或腹腔注射500mg/kg水提取物时也未发现死亡,但腹腔注射1000mg/kg时死亡率达60%。分别腹腔注射1000mg/kg当归、川芎、地黄提取物、
Siwutang is a formula composed of angelica, Chuanxiong, peony and earthworm. The author used Siwutang’s methanol and water extracts and three kinds of four kinds of crude drugs to take three combinations, namely: A: Angelica sinensis, peony, and rehmannia; B: Chuanxiong, peony, rehmannia; C: Chuanxiong, Angelica, rehmannia; D: The methanol extracts of Chuanxiong, Angelica sinensis, Paeonia lactiflora and the methanol extracts of Angelica sinensis, Rhizoma Chuanxiong, Paeonia lactiflora and Rehmannia glutinosa were studied in terms of the toxicity and lethal dose of radioactivity in normal mice. The results showed that no death was found when oral or intraperitoneal injection of 2000 mg/kg of Siwu Tang methanol extract was given to mice. No death was found when they were treated with 2000 mg/kg or 500 mg/kg water extract by intraperitoneal injection, but they were intraperitoneally injected with 1000 mg/kg. Mortality reached 60%. Intraperitoneal injection of 1000 mg/kg Angelica sinensis, Rhizoma Chuanxiong, Rehmannia glutinosa extract,