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目的:研究转运极早产儿发生支气管肺发育不良的危险因素。方法:对近5年转运的早产儿进行回顾性研究。收集患儿出生、转运时间、治疗及并发症的发生情况。使用多因素回归分析模型分析与BPD发生有关的危险因素。结果:总共134名胎龄小于32周的早产儿纳入研究。其中,33名因存在先天性心脏病或来院时纠正胎龄超过36周被剔除。101名早产儿纳入研究。最终95名存活到纠正胎龄36周。其中56名(58.9%)被诊断为BPD。出生体重、胎龄、转运时的日龄、肺表面活性物质的使用、败血症、动脉导管未闭、输血和机械通气与BPD的发生有关。转运时的日龄和输血次数是BPD发生的独立危险因素。结论:转运极早产儿的BPD发生率高。转运时间与BPD的发生有关。在缺乏管理经验的医院出生的极早产儿应该尽快转运至上级医院。
Objective: To study the risk factors for bronchopulmonary dysplasia in very premature infants with transshipment. Methods: A retrospective study was carried out on preterm infants transplanted in the past 5 years. Collect children’s birth, transit time, treatment and complications. Multivariate regression analysis was used to analyze the risk factors associated with BPD. Results: A total of 134 preterm infants less than 32 weeks gestational age were included in the study. Among them, 33 were removed due to the presence of congenital heart disease or correction of gestational age at the age of 36 weeks. 101 preterm infants were included in the study. The final 95 survived to correct gestational age 36 weeks. Of these, 56 (58.9%) were diagnosed with BPD. Birth weight, gestational age, age at transit, use of pulmonary surfactant, sepsis, patent ductus arteriosus, blood transfusions and mechanical ventilation are associated with BPD. The day of transfusions and the number of transfusions are independent risk factors for BPD. CONCLUSIONS: The incidence of BPD in very preterm infants with transport is high. Transit time and the occurrence of BPD. Very premature babies born in hospitals with no management experience should be transferred to higher level hospitals as soon as possible.