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目的应用伤残调整寿命年(DALYs)对山东省文登市居民恶性肿瘤疾病负担进行综合评价,为确定疾病防治重点、合理配置卫生资源提供依据。方法收集文登市2012年疾病监测系统恶性肿瘤死亡资料和恶性肿瘤发病登记报告系统中的资料,分析恶性肿瘤死亡水平和发病情况,并采用世界卫生组织(WHO)推荐的DALYs计算方法估算恶性肿瘤所致疾病负担。结果文登市2012年恶性肿瘤粗死亡率为195.01/10万,发病率为277.76/10万,恶性肿瘤所致DALYs损失为12 783个健康生命年,男性和女性的DALYs率分别为25.7/千人和18.2/千人;早死所致寿命损失年YLLs和残疾所致寿命损失年YLDs分别占DALYs的79.81%和20.19%;恶性肿瘤主要导致45~59岁人群的DALYs损失,占28.15%;恶性肿瘤疾病负担前10位为肺癌、肝癌、胃癌、结直肠癌、乳腺癌、白血病、脑癌、胰腺癌、淋巴瘤和宫颈癌。结论文登市居民恶性肿瘤疾病负担主要由早死所致,肺癌、肝癌和胃癌等主要癌症的疾病负担较重,应及时采取有效的干预措施。
Objective To evaluate the burden of malignant tumor in residents in Wendeng City, Shandong Province by DALYs, and provide the basis for determining the focus of disease control and rational allocation of health resources. Methods The data of malignant tumor deaths and the registration system of malignant tumors in the system of disease surveillance collected in Wendeng City in 2012 were collected to analyze the level of death and incidence of malignant tumors and to estimate the malignant tumors using the DALYs calculation method recommended by the World Health Organization Cause disease burden. Results In 2012, the average death rate of malignant tumors was 195.01 / 100 000, with an incidence rate of 277.76 / 100 000. The DALYs loss caused by malignant tumors was 12 783 healthy years of life. The DALYs rates of male and female were 25.7 / And 18.2 per thousand respectively; the annual YLLs due to premature death and YLDs due to disability caused 79.63% and 20.19% of the DALYs respectively; the malignant tumors mainly resulted in the loss of DALYs in the population aged 45-59, accounting for 28.15%; malignant tumors The top 10 diseases are lung cancer, liver cancer, stomach cancer, colorectal cancer, breast cancer, leukemia, brain cancer, pancreatic cancer, lymphoma and cervical cancer. Conclusions The burden of malignant tumor in Wendeng City is mainly caused by premature death. The major cancers such as lung cancer, liver cancer and gastric cancer have a heavy burden of disease. Effective interventions should be taken promptly.