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采用丙烯酸,2-丙烯酰胺-2-甲基丙磺酸为功能单体,N,N’-亚甲基双丙烯酰胺为交联剂,正十二醇、1,4-丁二醇及二甲基亚砜为致孔剂,偶氮二异丁腈为引发剂在原位聚合,制备出了以丙烯酰胺类强阳离子交换整体柱为核心的电渗泵。在乙腈-磷酸盐二元流动相体系下,考察了驱动电压,有机调节剂,盐浓度,pH对该泵流量的影响。流量与驱动电压呈线性关系(0.9991);当有机调节剂乙腈的浓度低于70%时,固定相溶胀为主要因素,流量随乙腈浓度的增加而有下降的趋势,但随着有机调节剂浓度的增加(>70%),此时粘度起主要作用,流量开始缓慢地增加;随着磷酸盐浓度逐渐增加,流量随之降低;在pH 3～9范围内,流量基本上保持恒定。
Acrylic acid, 2-acrylamide-2-methylpropane sulfonic acid as functional monomer, N, N’-methylenebisacrylamide as crosslinker, n-dodecanol, Methyl sulfoxide as porogen and azobisisobutyronitrile as initiator were polymerized in situ to prepare an electroosmotic pump with a core of acrylamide strong cation exchange monolith. Under acetonitrile-phosphate binary mobile phase system, the effects of driving voltage, organic regulator, salt concentration and pH on the pump flow rate were investigated. The linear relationship between the flow rate and the driving voltage (0.9991). When the concentration of acetonitrile was lower than 70%, the swelling of the stationary phase was the main factor. The flow rate decreased with the increase of acetonitrile concentration. However, with the concentration of organic modifier (> 70%). At this time, the viscosity plays a major role and the flow rate begins to increase slowly. As the phosphate concentration gradually increases, the flow rate decreases. In the range of pH 3 ~ 9, the flow rate is basically constant.