2013-2015年北京市怀柔区病毒性腹泻病原及流行病学分析

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目的了解2013-2015年怀柔区病毒性腹泻病原学结果及流行特征,为其防治提供针对性的科学依据。方法对2013年4月-2015年3月怀柔区哨点医院肠道门诊散发性腹泻病例进行轮状病毒、诺如病毒、肠道腺病毒和星状病毒监测,并对监测结果进行描述流行病学分析。结果共检测264例腹泻患者标本,117例检出至少一种病毒感染,检出率为47.6%。四种病毒阳性检出率顺序依次为诺如病毒(23.6%)、轮状病毒(21.1%)、肠道腺病毒(11.8%)、星状病毒(4.5%)。男女性别比为1.7:1,男女性别间阳性检出率差异无统计学意义。各年龄段人群均能感染腹泻病毒,2岁以内婴幼儿检出率最高。诺如病毒流行高峰在10-11月,轮状病毒高峰从11月-次年的2月,肠道腺病毒发病季节性不明显,星状病毒以低流行散发为主。结论怀柔区2013-2015年散发腹泻患者诺如病毒和轮状病毒感染率较高,流行季节主要在冬春季。应加强对病毒性腹泻的监测,预防暴发疫情尤其是诺如病毒感染的发生。 Objective To understand the etiological and epidemiological characteristics of viral diarrhea in Huairou District from 2013 to 2015 and provide scientific basis for its prevention and treatment. Methods The rotavirus, norovirus, enterovirus and astrovirus were monitored in the sporadic outbreak diarrhea in sentinel hospital of sentinel hospital in Huairou from April 2013 to March 2015. The surveillance results were used to describe the epidemic Analysis. Results A total of 264 cases of diarrhea patients were detected, 117 cases detected at least one virus infection, the detection rate was 47.6%. The positive rates of four viruses were Norovirus (23.6%), rotavirus (21.1%), Enteric adenovirus (11.8%) and Astrovirus (4.5%). The ratio of male to female was 1.7: 1, there was no significant difference in the positive detection rate between male and female. The diarrhea virus can infect people of all ages, and the highest detection rate of infants and children within 2 years of age. The highest prevalence of Norovirus in October-November, the peak rotavirus from November to February of the following year, seasonal onset of intestinal adenovirus is not obvious, astrovirus circulating with low prevalence. Conclusions The infection rates of norovirus and rotavirus in diarrhea patients in Huairou district during 2013-2015 are higher, and the epidemic season is mainly in winter and spring. Monitoring of viral diarrhea should be strengthened to prevent outbreaks, especially Norovirus infections.
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