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应用静脉色氨酸耐量试验检测118例病理确诊的慢性肝病及77例对照者的肝功能,显示其对慢性迁延性肝炎的阳性率96.6%,慢性活动性肝炎95.5%,肝硬化100%。统计敏感度90.6%,特异度92.2%,阳性预测值94.6%,阴性预测值86.5%,诊断准确率91.2%。55例患者自身对照证实本试验对慢迁肝和慢活肝的敏感性优于常规肝功能试验、胆酸测定和吲哚氰绿试验。
The venous tryptophan tolerance test was used to detect the liver function of 118 pathologically confirmed chronic liver disease and 77 controls. The positive rate was 96.6% for chronic persistent hepatitis, 95.5% for chronic active hepatitis and 100% for cirrhosis. The statistical sensitivity was 90.6%, the specificity was 92.2%, the positive predictive value was 94.6%, the negative predictive value was 86.5%, and the diagnostic accuracy rate was 91.2%. The self-control of 55 patients confirmed that this test is superior to routine liver function test, cholic acid assay and indocyanine green assay for slow-moving and slow-moving liver.