目前,国内生产凝血酶主要是用动物血浆制备,再经激活物激活而形成凝血酶。凝血酶在临床上应用广泛,常以干粉或溶液局部涂于伤口及手术处,控制毛细血管血液渗出,多用于骨出血、扁桃体摘除和拨牙时止血等。有时也可口服,用于胃和十二脂肠出血。凝血酶局部止血效果好,无副作用。目前凝血酶的应用范围正在日渐扩大,由单纯的局部外敷发展到外科手术、耳鼻喉、口腔、妇产、泌尿及消化道等部位出血的止血,亦可作为多种外用止血药物的重要原料,其止血效果优 At present, the main production of thrombin in domestic animal plasma preparation, and then activated by the activator to form thrombin. Thrombin is widely used clinically, often applied locally to the wounds and surgical sites of dry powder or solution to control capillary blood exudation, used for bone hemorrhage, tonsillectomy and dial teeth to stop bleeding. Sometimes also oral, for the stomach and duodenal bleeding. Thrombin local hemostatic effect, no side effects. At present, the scope of application of thrombin is gradually expanding. From simple topical external application to hemostasis in surgery, ENT, oral cavity, obstetrics and gynecology, urinary and gastrointestinal bleeding, etc., it can also be used as an important raw material for a variety of topical hemostatic drugs, Its hemostatic effect is excellent