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为进一步探讨参附注射液抗休克机制，本文观察了参附注射液对鼠肾缺血再灌注模型超氧化物歧化酶（ＳＯＤ）及组织形态的影响。结果显示，与缺血再灌组相比，参附注射液组肾外髓水肿明显减轻（Ｐ＜０．０１），ＳＯＤ活性明显增高（Ｐ＜０．０１）。提示保护ＳＯＤ活性、降低脂质过氧化反应的作用是参附注射液抗休克的机制之一。
To further explore the anti-shock mechanism of Shenfu injection, the effects of Shenfu injection on superoxide dismutase (SOD) and histomorphology of rat kidney ischemia-reperfusion model were observed. The results showed that the extramedullary marrow edema in the Shenfu injection group was significantly reduced (P<0.01), and the SOD activity was significantly increased (P<0.01) compared with the ischemia-reperfusion group. It suggests that the protection of SOD activity and the reduction of lipid peroxidation are one of the mechanisms of Shenfu injection anti-shock.