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目的:探讨晚期上颌窦鳞状细胞癌眶侵犯患者手术中眶内容物的处理。方法:将46例有眶侵犯的晚期上颌窦鳞状细胞癌手术患者分为眶骨壁侵犯组、眶骨膜侵犯组、眶内侵犯组,随访2、3、5年的生存率和2年复发率,并加以统计分析。结果:2、3、5年生存率和2年复发率眶骨壁侵犯组分别为65.2%、55.6%、46.7%和38.1%;眶骨膜侵犯组分别为57.1%、50.0%、45.5%和53.8%;眶内侵犯组分别为44.4%、37.5%、37.5%和62.5%。3组生存率依次降低,复发率依次升高,但均差异无统计学意义(均P>0.05)。结论:晚期眶侵犯上颌窦鳞状细胞癌患者的手术中对有眶骨壁或眶骨膜侵犯者保留眶内容物是可以考虑的。
Objective: To investigate the treatment of orbital contents in patients with advanced maxillary sinus squamous cell carcinoma during orbital invasion. Methods: Forty-six patients with advanced maxillary sinus squamous cell carcinoma with orbital invasion were divided into orbital and periorbital invasion group, orbital periosteum invasion group and orbital invasion group. The survival rate at 2, 3 and 5 years and the 2-year follow-up Rate, and statistical analysis. Results: The 2-year, 3-year and 5-year survival rates and 2-year recurrence rates were 65.2%, 55.6%, 46.7% and 38.1% in the orbital-wall invasion group and 57.1%, 50.0%, 45.5% and 53.8 %; Orbital invasion group were 44.4%, 37.5%, 37.5% and 62.5% respectively. The survival rates of the three groups decreased in turn and the recurrence rates increased in turn, but the differences were not statistically significant (all P> 0.05). CONCLUSIONS: The preservation of the orbital contents of the orbital wall or periorbital periost in the patients with advanced orbital invasion of squamous cell carcinoma of the maxillary sinus may be considered.