目的研究氨氯地平(络活喜)在治疗顽固性高血压患者的过程中的临床效果。方法选择顽固性高血压患者60例,随机分为观察组和对照组各30例,在治疗的过程中对照组使用贝那普利10mg1次/d,氢氯噻嗪12.5 mg 2次/d;观察组患者在对照组患者治疗的基础上同时给予患者服氨氯地平10 mg,1次/d,两组患者的治疗时间均为8周,完成治疗之后对比两组患者的治疗效果。结果观察组患者的治疗情况明显由于对照组患者,患者的显效率和治疗有效率等均高于对照组患者,两组相比,差异有统计学意义(P<0.05)。结论在治疗顽固性高血压的过程中,可以联合使用氨氯地平进行治疗,提高患者的临床治疗效果,值得在临床上进行推广使用。 Objective To study the clinical effect of amlodipine (Luohuoxi) in the treatment of patients with refractory hypertension. Methods Sixty patients with refractory hypertension were randomly divided into observation group and control group, with 30 cases in each group. The control group was treated with benazepril 10 mg once daily and hydrochlorothiazide 12.5 mg twice daily. The patients in observation group Patients in the control group were treated with amlodipine 10 mg once daily on the basis of the treatment. The treatment time of both groups was 8 weeks. After the treatment was completed, the therapeutic effect was compared between the two groups. Results Obviously, the treatment of patients in the observation group was significantly higher than that in the control group because of the patients in the control group. The differences between the two groups were statistically significant (P <0.05). Conclusion In the treatment of intractable hypertension, amlodipine can be used in combination to improve the clinical effect of patients, which is worth to be popularized in clinic.