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目的调查尿中大肠埃希氏菌耐药特点，讨论用药习惯对细菌产生耐药性的影响。方法常规方法进行中段尿细菌培养和鉴定，Ｋ－Ｂ法进行药敏试验。结果发现尿中与非尿中大肠埃希氏菌有很大差异，它们分离情况和耐药性不同。磺胺和氟哌酸等常用于泌尿系感染治疗的药物，对尿中大肠埃希氏菌的耐药率明显高于其它部位分离的大肠埃希氏菌，而其它抗生素的耐药率区别不大。结论不同部位的感染用药习惯不同，这可能对耐药性的产生有很大的影响
Objective To investigate the drug-resistant characteristics of Escherichia coli in urine and to discuss the influence of drug-use on bacterial resistance. Methods The middle method of urine culture and identification of bacteria, K-B method for susceptibility testing. The results showed that urinary and non-urinary Escherichia coli are very different, their isolation and resistance are different. Sulfanilamide and norfloxacin and other drugs commonly used in the treatment of urinary tract infection, the resistance rate of Escherichia coli in urine was significantly higher than that of Escherichia coli isolated from other parts, while the difference was not significant in other antibiotics . Conclusions Infections of different parts of the habit of using different drugs, which may have a significant impact on drug resistance