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作者通过脉冲多普勒超声并结合临床、生化以及内镜参数,对50例代偿期肝硬化患者追踪观察,以期前瞻性评价门脉血液动力学对预后的价值。病人和方法:50例肝硬化患者(男28,女22,年龄22～77岁,平均58岁)。诊断均经组织学证实。1984年9月至12月,对所有病例均予临床、常规肝功能试验、多普勒超声和上消化道内镜检查,并随访至1990年12月(除死亡病例外)。按白蛋白、胆红素、凝血酶原活性、腹水和脑病之总和作Child-Pugh评分。结果:至观察结束,已有25例死于与肝病有关的并发症。单变量分析表明Child-Pugh评分<7的患者存
By pulse Doppler ultrasound combined with clinical, biochemical and endoscopic parameters, 50 patients with compensated cirrhosis were followed up in order to prospectively evaluate the value of portal hemodynamics prognosis. Patients and Methods: Fifty patients with cirrhosis (male 28, female 22, aged 22-77 years, mean 58 years). The diagnosis was confirmed by histology. From September to December 1984, clinical, routine liver function tests, Doppler ultrasound and upper gastrointestinal endoscopy were performed on all cases and were followed up to December 1990 except for deaths. The Child-Pugh score was calculated as the sum of albumin, bilirubin, prothrombin activity, ascites and encephalopathy. Results: By the end of observation, 25 patients had died of liver-related complications. Univariate analysis showed that patients with Child-Pugh scores <7 were excluded