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作者对１０９例胎膜早破患者血清Ｃ－反应蛋白（Ｃ－ＲＰ）进行了测定。结果为：Ｃ－ＲＰ＜５ｍｇ／Ｌ组，绒毛膜炎的发生率明显低于５～１０ｍｇ／Ｌ组，（Ｐ＜０．０５）；Ｃ－ＲＰ＞１０ｍｇ／Ｌ的２９例有２８例（９６．５５％）发生绒毛膜炎，Ｃ－ＲＰ＜５ｍｇ／Ｌ组的胎心率异常，羊水混浊的发生率明显低于５～１０ｍｇ／Ｌ组和＞１０ｍｇ／Ｌ组（Ｐ＜０．０１），而新生儿窒息的发生卒＜５ｍｇ／Ｌ组和５～１０ｍｇ／Ｌ组相比无统计学意义（Ｐ＞０．０５），而＞１０ｍｇ／Ｌ时则差异显著（Ｐ＜０．０１）。胎膜早破至分娩时间，＜２４ｈ的Ｃ－ＲＰ无明显变化，而≥２４ｈ组Ｃ－ＲＰ值５～１０ｍｇ／Ｌ者明显高于＜２４ｂ组（Ｐ＜０．０１），Ｃ－ＲＰ＞１０ｍｇ／Ｌ者从２４ｈ后逐渐增高（Ｐ＜０．０１），其绒毛膜炎的发生率则随着破膜时间的延长而逐渐增加（（Ｐ＜０．０２～０．００５），当≥４８ｈ，其发生率为９２．８６％。
The author of 109 cases of premature rupture of membranes in patients with serum C-reactive protein (C-RP) were measured. The results showed that the incidence of choriomyelitis in C-RP group was significantly lower than that in 5-10 mg / L group (P <0.05), while in C-RP group (10 mg / L), there were 28 cases 96.55%) had chorioamnionitis. The fetal heart rate was abnormal in C-RP <5mg / L group, the incidence of amniotic fluid opacity was significantly lower than that in 5 ~ 10mg / L group and> 10mg / L group ), While the incidence of neonatal asphyxia <5mg / L group and 5 ~ 10mg / L group was no significant difference (P> 0.05), and> 10mg / L when the difference was significant ). There was no significant change of C-RP in 24h after premature rupture of membranes and C-RP of 5 ~ 10mg / L in ≥24h group was significantly higher than that in <24b group (P <0.01) The incidence of chorioamnion gradually increased with the prolongation of rupture time (P <0.02-0.005). When the level of ≥10mg / L increased from 24h (P <0.01) 48h, the incidence was 92.86%.