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作者对120例低原始细胞型白血病(Oligo-blastic leukemia)进行了分析。此型白血病的诊断标准是:①骨髓中原粒细胞中度增高,原粒多于7％,原粒加早幼粒≤50％;②骨髓再生不良;③周围血中白细胞少于2万。 120例中,2/3的年龄在60～80岁,15例在50岁以下。男70％,女30％。15例尚存活,51例已死亡,54例失去联系。27例病程超过2年,13例超过或长达3年。这13例中4例尚存活,其中1例已7年,9例存活3～6年后死亡或失去联系。随访66例明确知道其结局者,中数存活期为14个月。35例的死因分析:22例(63％)死于出血或感染,5例(14％)死于急性白血病发作,8例(23％)死于其他原因。
The authors analyzed 120 cases of low-grade leukemia (Oligo-blastic leukemia) were analyzed. This type of leukemia diagnostic criteria are: ① moderate increase in bone marrow neutrophils, more than 7% of the original particles, the original particles plus promyelocytic ≤ 50%; ② poor bone marrow regeneration; ③ peripheral blood leukocytes less than 20,000. Of the 120 patients, two thirds were 60 to 80 years old and 15 were under 50 years. Male 70%, female 30%. Fifteen survived, 51 died, and 54 lost contact. 27 cases of more than 2 years duration, 13 cases over or up to 3 years. Of the 13 patients, 4 survived, 1 of them survived 7 years and 9 died or lost contact after 3 to 6 years of survival. 66 patients were followed up for a definite understanding of their outcome, the median survival of 14 months. Mortality in 35 patients: 22 (63%) died of bleeding or infection, 5 (14%) died of acute leukemia and 8 (23%) died of other causes.