论文部分内容阅读
细胞内钙信使系统正常调节的失控为许多毒物作用的共同途径,因此,钙信使系统中的各环节,包括细胞内磷酸化酶a、钙调素(CaM)的活性及依赖CaM的一系列酶如钙-镁-腺嘌呤核苷三磷酸酶(Ca~(++)-Mg~(++)-ATPase)等都可能成为毒物作用的靶部位。CCl_4是一种公认的
The loss of normal regulation of the intracellular calcium messenger system is a common pathway for many toxicological effects. Therefore, various aspects of the messenger of calcium, including intracellular phosphorylase a, calmodulin (CaM) activity and a series of CaM-dependent enzymes Such as calcium - magnesium - adenosine triphosphatase (Ca ~ (++) - Mg ~ (++) - ATPase) may become the target site of toxic effects. CCl_4 is a recognized one