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目的探索应用氩氦外科冷冻系统结合脑立体定向外科治疗脑胶质瘤的手术疗效。方法使用CRW立体定向仪，行头顿计算机体层摄影扫描（CT）确定脑胶质瘤中心及边缘点坐标。以氩氦超冷治疗探针在限定靶区进行冷冻－复温－冷冻治疗4例复发性胶质瘤。结果1例直径4．5cm的颞部肿瘤行钻孔肿瘤中心靶点冷冻治疗；余3例直径8～15cm枕顶部肿瘤行主体定向等体积切除手术，术中冷冻后切除冷冻瘤组织。术后CT扫描显示：3例肿瘤组织及肿瘤边缘1cm范围被切除，术后无出血及明显水肿；1例直接冷冻治疗后3周复查见病灶染色消失，CT密度下降，呈软化改变。术后1例轻偏瘫加重，对症处理后恢复，1例头皮切口愈后不良，经皮瓣转移后愈合。结论立体定向引导氩氦超冷刀治疗脑胶质瘤，能较彻底切除肿瘤，手术侵袭性小，安全且易于操作，具有较强的临床应用价值；但此操作技术还不尽完善，远期疗效还有待进一步观察。
Objective To explore the surgical treatment of glioma with argon-helium surgical cryosurgery and brain stereotactic surgery. Methods CRW stereotaxic apparatus was used to determine the center and edge coordinates of gliomas by VTA computed tomography (CT). Four cases of recurrent glioma were treated with cryogenic-rewarming-cryogenic treatment with argon-helium supercooling probes in defined target areas. Results One case of tumor with a diameter of 4.5 cm was treated with cryogenic treatment of the center of the tumor. Another three cases with a diameter of 8-15 cm were treated with isobaric volumetric resection. The frozen tissue was removed after surgery. Postoperative CT scan showed that 3 cases of tumor tissue and the edge of the tumor were excised within 1cm, no hemorrhage and obvious edema occurred after the operation. One case was retreated 3 weeks after direct cryotherapy, the lesions disappeared and the CT density decreased, showing a softening change. One case of postoperative hemiplegia aggravate symptomatic recovery, one case of scalp incision poor prognosis, healed after transposition of the flap. Conclusion Stereotactic guide argon-helium supercooled knife treatment of glioma, more complete removal of the tumor, invasive surgery, safe and easy to operate, with strong clinical value; but this operation is not perfect, long-term The efficacy remains to be further observed.