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2017年12月至2018年12月，在天津医科大学总医院健康管理中心定期健康体检的3 509名研究对象中，曾罹患肿瘤、罹患慢病和健康对照三组分别有399、1 555、1 555名。年龄为（55.87±11.98）岁，男性占31.38%。慢病组MS患病率（42.44%）高于曾罹患肿瘤组（34.59%）和健康对照组（18.65%）（n P<0.001）。与健康对照组相比，曾罹患肿瘤组和慢病组MS患病风险n OR（95%n CI）值分别为2.13（1.61~2.83）和2.85（2.23~3.66）；曾罹患乳腺癌和甲状腺癌MS患病风险n OR（95%n CI）值分别为3.56（2.04~6.21）和2.77（1.46~5.25）。n “,”From December 2017 to December 2018, 3 509 subjects who had regular physical examination in Health Management Center, Tianjin Medical University General Hospital were enrolled in our study, including 399 cancer patients, 1 555 chronic disease patients, and 1 555 healthy control, respectively. The mean age was (55.87±11.98) years, and 31.38% were men. The prevalence of MS among chronic disease group (42.44%) was higher than that of cancer group (34.59%) and healthy control group (18.65%) (n P<0.001). Compared with healthy control group, then OR (95%n CI) values of MS risk in cancer group and chronic disease group were 2.13 (1.61-2.83) and 2.85 (2.23-3.66), respectively; the n OR (95%n CI) values of MS risk were 3.56 (2.04-6.21) and 2.77 (1.46-5.25) in breast cancer and thyroid cancer, respectively.n