全膝关节置换术( total knee arthroplasty，TKA )是一种治疗骨关节炎的有效方法。近年来，为了提高 TKA 的假体的位置精度，手术机器人、个性化手术导板、术前规划软件和计算机导航系统被广泛使用。重建良好的下肢力线被认为是判断 TKA 是否成功的标准之一。有研究表明，手术机器人、个性化手术导板、术前规划软件和计算机导航系统的使用可以提高手术效果，延长假体使用寿命。但也有另外一些研究表报道了以上方法对经验充分、手术数量多的医生并没有显著提高手术效果。此综述的目的是进一步深入理解手术机器人、个性化手术导板、术前规划软件和计算机导航系统对膝关节手术效果的影响。目前以上方法可以满足 TKA 的指标(如下肢力线重建)，但是仍需要关于长期手术效果和患者满意度的随访报道来进一步确认手术机器人、个性化手术导板、术前规划软件和计算机导航系统的有效性。“,”Total knee arthroplasty ( TKA ) is one of the reliable options for patients with end stage osteoarthritis. The robots, patient speciifc cutting guides, preoperative software and computer-assisted surgery have been introduced in order to improve the accuracy of operative prosthesis positioning in TKA. Therefore, optimal restored normal kinematics can be achieved. Overall limb alignment is taken as critical standard to obtain a successful outcome of TKA. Some studies suggested that the improvements in treatments for TKA may lead to optimal clinical outcomes and longer implant survivorship, while some other studies suggest that these technologies may not make a difference for well trained and high volume surgeons. To better understand the subtle nature of such treatments, the effect of robots, patient speciifc cutting guides, preoperative software and computer-assisted surgery have been reviewed. Outcomes of the total knee arthroplasty and future trend outlook also have been discussed. Although some criteria of the TKA ( i.e. lower limb alignment ) can be fuliflled via these technologies, long-term follow-up studies on patients’ satisfaction, complications and clinical outcomes are needed.