口眼干燥综合征(Sjogren)为一种原因不明的少见疾病。临床以干燥性角膜炎及口腔干燥,唾液分泌减少为特点,其往往与胶原性疾病相重叠而形成重叠综合征。我们遇到一例报告如下: 王××,女22岁,未婚,住院号122189,患者于五年前开始感到咽喉痛,口干,没有唾液,吃馍时需要饮水才能咽下。眼干无泪,且分泌物增多,视物模糊,有异物感。 Sjogren is a rare disease of unknown cause. Clinically dry keratitis and dry mouth, salivary secretion is characterized by reduced, which often overlap with the collagen disease and the formation of overlapping syndrome. We encountered a case report as follows: Wang × ×, 22-year-old woman, unmarried, hospital number 122189, the patient began to feel sore throat five years ago, dry mouth, no saliva, eating water when you need to drink water to swallow. Dry eyes and tears, and increased secretions, blurred vision, foreign body sensation.