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恶性肿瘤细胞群内极少数具有无限自我更新潜能导致肿瘤发生和复发的细胞被称为肿瘤干细胞。研究证实了头颈部鳞状细胞癌中肿瘤干细胞的存在,它们是恶性肿瘤发生和复发的根源。头颈部恶性肿瘤中病死率最高的是头颈部鳞状细胞癌,而头颈部鳞状细胞癌干细胞的研究主要集中在细胞表面抗原的识别,目前研究较多的头颈部鳞状细胞癌的表面抗原标志物有CD133和CD44以及其他一些标志物。肿瘤干细胞的研究将使人们能够识别治疗的标靶,并将有可能使患者治愈。
A very small number of malignant tumor cell populations with unlimited potential for self-renewal that lead to tumorigenesis and recurrence are called tumor stem cells. Studies confirm the existence of cancer stem cells in head and neck squamous cell carcinoma, which are the source of malignancy and relapse. Head and neck cancer is the highest mortality of head and neck squamous cell carcinoma, and head and neck squamous cell carcinoma stem cell research focuses on the identification of cell surface antigen, the current study more head and neck squamous cell The cancer surface antigen markers are CD133 and CD44 as well as some other markers. Research on cancer stem cells will enable people to identify the target of treatment and will likely cure the patient.