目的:分析小儿支原体肺炎临床特点,总结诊治经验。方法:2012年2月~2014年7月,某基层卫生服务站收治21后经确诊的小儿支原体肺炎,入院后,均详细询问病史、既往诊断与治疗史,行血常规检查、血沉检查,C反应蛋白、肝肾功能检测、呼吸道病原学检测,均给予支持治疗、对症治疗,据药敏实验结果,均给予阿奇霉素序贯治疗,若诊断为难治性支原体肺炎,转院治疗。结果:7例转上级医院治疗,总住院时间4~40d、平均(10.1±5.1)日;痊愈17例、有效4例;退热时间2~43d、平均(3.0±2.1)d,咳嗽消失时间3~18d、平均(9.2±4.4)d,啰音消失时间1~14d、平均(6、0±3.2)d。结论:小儿支原体肺炎确诊难度大,基层医院收治高热小儿肺炎,应首先做好病原体检查,积极对症治疗,据经验或药敏实验给予敏感抗生素治疗,首选阿奇霉素,一般可或较好疗效,对于1周内仍未获得痊愈者、有肺外病变,应提高警惕,及时转上上级医院治疗。 Objective: To analyze the clinical features of children with mycoplasma pneumonia and to summarize the experience of diagnosis and treatment. Methods: From February 2012 to July 2014, a grass-roots health service station was diagnosed with mycoplasma pneumonia in children after 21 years. After admission, all patients were asked for history, previous diagnosis and treatment history, blood routine examination, erythrocyte sedimentation rate test, C Reactive protein, liver and kidney function tests, respiratory aetiology, were given supportive treatment, symptomatic treatment, according to drug susceptibility test results were given azithromycin sequential treatment, if the diagnosis of refractory mycoplasma pneumonia, transfer treatment. Results: 7 cases were transferred to higher level hospitals, the total length of hospital stay was 4 ~ 40 days, with an average of (10.1 ± 5.1) days; 17 cases were cured and 4 cases were effective. The average time of fever relief was 2 ~ 43 days (3.0 ± 2.1) days, 3 ~ 18 days, with an average of (9.2 ± 4.4) days and rales disappearing time of 1 ~ 14 days with an average of (6,0 ± 3.2) days. Conclusions: Mycoplasma pneumonia is very difficult to diagnose in children. Primary hospital should be treated with pathogens and positive symptomatic treatment. Highly sensitive antibiotics should be given according to experience or susceptibility test. Azithromycin is the first choice, which may be better or worse. Were still not recovered within the week, extrapulmonary disease should be vigilant, promptly transferred to the higher hospital for treatment.