在水相中建立了一种简单实用、经济环保的实现含氮杂环化合物N-芳基化反应的催化体系.实验发现以廉价的Cu2O为催化剂,价廉、易获得的8-羟基喹啉为配体,n-Bu4NBr为相转移催化剂,在水相中100℃下含氮杂环化合物与卤代芳烃顺利反应生成C—N偶联产物,得到中等及优良的产率. A simple, practical and economical environment-friendly catalytic system for the N-arylation of nitrogen-containing heterocyclic compounds was established in the aqueous phase.It was found that the inexpensive, readily available 8-hydroxyquinoline As the ligand and n-Bu4NBr as phase transfer catalyst. The reaction of the nitrogen-containing heterocyclic compound with the halogenated aromatic compound in the aqueous phase at 100 ° C smoothly yields the C-N coupling product, resulting in moderate and excellent yields.