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目的:观察中药疣毒净制剂治疗宫颈高危型人乳头瘤病毒(HR-HPV)感染的临床疗效及护理方法。方法:将2014年1月至2015年12月广东省中医院大学城医院门诊诊治的宫颈HR-HPV感染患者40例随机分成治疗组和对照组各20例;治疗组用中药疣毒净制剂外用,对照组用生理盐水外用,每周治疗3次,治疗3个月共19次,于第3次月经干净后复查,观察HR-HPV转阴率及药物的不良反应。结果:治疗组HR-HPV的病毒清除率明显高于对照组(55%vs 20%,P<0.01),两组均未见不良反应。结论:外用疣毒净制剂对HR-HPV感染宫颈病变有较好的治疗效果,且无毒副作用,建议临床推广应用。
Objective: To observe the clinical curative effect and nursing method of Chinese wart drug net preparation in treatment of cervical high risk human papillomavirus (HR-HPV) infection. Methods: From January 2014 to December 2015, 40 cases of cervical HR-HPV infection from outpatient department of Guangdong University Hospital of Traditional Chinese Medicine were randomly divided into treatment group (20 cases) and control group (20 cases). The treatment group , The control group with saline for external use, treatment three times a week for 3 months, a total of 19 times, after the third menstrual clean reexamination observed HR-HPV negative rate and adverse drug reactions. Results: The HR-HPV in the treatment group was significantly higher than that in the control group (55% vs 20%, P <0.01). No adverse reactions were observed in both groups. Conclusion: The external wart drug net preparation has a good therapeutic effect on HR-HPV infection of cervical lesions, and has no toxic and side effects. It is recommended for clinical application.