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血镍含量反映的是最近几天接触可溶性镍化合物的情况。血浆镍的半寿期为２０小时～３４小时。许多情况都能影响血镍含量。血镍水平在接触可溶性镍的工人体内较非接触者高。尿样在测定新近镍接触方面因为它方便、分析准确及灵敏感而优于血样。尿镍含量和急性羟酰镍中毒严重程度呈正相关。肺组织中镍含量积聚较其它组织高。镍分析技术的改进使镍的测定更为准确可靠。
Nickel content reflects the nickel exposure to soluble nickel compounds in recent days. Plasma nickel half-life of 20 hours to 34 hours. In many cases, blood nickel levels can be affected. Blood nickel levels were higher in nonsmokers compared with workers exposed to soluble nickel. Urine samples are superior to blood samples in determining recent nickel contact because they are convenient, accurate, and sensitive to analysis. Urine nickel content and the severity of acute nickel oxyhalide poisoning was positively correlated. Nickel accumulation in lung tissue is higher than in other tissues. The improvement of nickel analysis technology makes the determination of nickel more accurate and reliable.