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本文利用核酸杂交技术，对人原发性喉癌及其转移灶中的Ｃ－ｍｙｃ原癌基因的扩增情况进行了研究，结果发现１１例喉癌和１２例颈转移癌中，分别有８例（７２．７％）和７例（５８．３％）Ｃ－ｍｙｃ基因扩增１．５～１６．０倍。提示Ｃ－ｍｙｃ基因可能参与喉癌的发生及其演进机制。
In this paper, the use of nucleic acid hybridization in human primary laryngeal cancer and its metastasis of C-myc protooncogene amplification was found in 11 cases of laryngeal cancer and 12 cases of cervical cancer, respectively, 8 Cases (72.7%) and 7 cases (58.3%) C-myc gene amplification of 1.5 to 16.0 times. These results suggest that C-myc may be involved in the pathogenesis and progression of laryngeal carcinoma.